Below is a preliminary study conducted by the Washington University School of Medicine that clearly shows users of glucosamine experienced "significant reduction" of pain and suffered less radiographic narrowing (cartiliage deterioration) of the knee.
Long-term effects of glucosamine sulfate on osteoarthritis progression
A randomized, double-blind, placebo-controlled prospective clinical trial
Reported by: Richard Brasington, Washington University School of Medicine, St Louis, USA
In the study, the group treated with glucosamine sulfate, 1500 mg/day, suffered less radiographic narrowing of the knee joint (0.06 mm versus 0.31 mm) than the placebo group. Furthermore, the glucosamine treated group experienced significant reduction of symptoms (WOMAC pain and function subscales). The authors conclude that glucosamine sulfate slows the progression of osteoarthritis of the knee, in addition to relieving the symptoms.
The identification of a medication capable of retarding the progression of osteoarthritis would be a revolutionary development in rheumatic therapeutics. The major limitation of the design of this study is the use of standard weight-bearing views of the knee to measure joint space narrowing. Such views are not ideal for assessing the femoral-tibial joint space, and difficulty in reproducing the precise orientation of the joint space make serial comparisons problematic. This undermines the significance of the apparent differences between the two groups over time, especially in view of differences of tenths of millimeters. Superior positioning techniques, such as the semi-flexed view described by Buckland-Wright et al (see additional information), should be used in future studies to attempt to confirm this observation. Nonetheless, this paper heightens expectations that treatment to prevent the progression of osteoarthritis may be on the horizon, and provides evidence the use of glucosamine sulfate for osteoarthritis of the knee.
Glucosamine not worked for you as well as you thought it might? Read new research on how glucosamine can be made ten times as effective.
If you have arthritis, we highly recommend trying Syn-flex®. Syn-flex® is a fast-acting, high quality osteoarthritis formula for humans and pets. This premium quality product is formulated with liquid glucosamine sulfate, glucosamine hydrochloride, chondroitin sulfate, and nine other arthritis-fighting ingredients. Syn-flex® will not only ease your pain quickly, it will slow the progression of your osteoarthritis. Learn more about Syn-flex® here.
J.R. Rogers is the founder and President of Activex America, Inc. makers of Liquid Glucosamine Formula Syn-flex®
The author's statements have not been evaluated by the Food and Drug Administration and are not provided to diagnose any disease or to suggest that liquid glucosamine and chondroitin will treat, cure, or prevent any disease.
|
