Liquid Glucosamine for Arthritis Resources

Arthritis Pain Relief Product Comparison

Glucosamine for arthritis is very beneficial and this has been proven to work in numerous double-blind, placebo-controlled studies. In these studies, liquid glucosamine has been shown to assist in the rehabilitation of cartilage, reducing the progression of osteoarthritis, and significantly lessening the pain from arthritis.

When your health is at stake, you need to know how to choose between competing products and see through the marketing hype. There are six factors that you need to take into your decision making process before purchasing any glucosamine product.

These are:

  • Amount of glucosamine per daily dose
  • Type of glucosamine
  • Quality of ingredients
  • Delivery system
  • Synergistic ingredients
  • Price per day

Quick Tip:

  • It is very important to compare price per day and not price per product, as many companies try to fool you by providing 60 capsules or 32 oz. and not telling you until after you purchased that you must use 6 capsules or 2 oz. per day.

Capsules or Liquid?

Did you know that nutritional supplements like glucosamine are usually absorbed faster and become bioavailable quicker in liquid form than in pill form? In addition, with pills you run the risks that binders and fillers are in the pills, reducing the actual amount of the beneficial supplement, causing the pill to be less absorbable and less bioavailable than liquid glucosamine and as a result, passing through your digestive system without having the intended beneficial effect on your osteoarthritis.The outside coating of pills and capsules can cause a barrier in the breakdown of the supplement, meaning that the supplement may pass through your digestive track before it is able to dissolve fully.

Comments about our rating system
Clinical studies have indicated that liquid glucosamine is absorbed more quickly than in pill or capsule form.

There are websites being operated on the internet that purport to be neutral in their product evaluations. However, most fail to alert consumers that in fact, they are promoting their own products without fully disclosing their interest. It is our feeling that this is unfair to the consumer. For that reason, we want to advise you that this evaluation is being provided by Synflex America, Inc., the makers of Synflex®. We have had years of experience in this industry and our interest is in providing you with information that we hope will be useful in making an informed decision about the product you select. We also suggest that you take a careful look at product comparisons on other websites and try to ascertain who is funding each such website. If someone is failing to disclose their identity on an endorsement, then they may be willing to hide other information important to your purchasing decision.

First, let's review the leading liquid Glucosamine formulas:

Synflex® 1500

Amount of Glucosamine per daily dose: 1,500 mg
Type of Glucosamine: both Glucosamine Sulfate and Glucosamine HCL
Quality of Glucosamine: Pharmaceutical Quality
Delivery System: Liquid
Synergistic Ingredients:
White Willow Bark for greater anti-inflammatory impact; Chrondroitin Sulfate, Boswellin, Yucca Powder, Manganese, Ascorbate, Bromelain, Vitamin C, Omega 3 Fatty Acids, Omega 6 Fatty Acid, Vitamin A, Vitamin E.
Price per day: $.91
Rating Rationale: More Glucosamine to an already successful formula and delivered in liquid form to ensure maximum absorption. The 11 synergistic ingredients that have all been shown to aid in the fight against arthritis make this a great product. Plus a great naturally Orange flavor!

* Doctor Recommended

Syn-flex® 1500 is not recommended for pets. Use only the original formula Synflex® for pets or the beef flavored Synflex® for pets.


Amount of Glucosamine per daily dose: 1,250 mg
Type of Glucosamine: both Glucosamine Sulfate and Glucosamine HCL
Quality of Glucosamine: Pharmaceutical Quality
Delivery System: Liquid
Synergistic Ingredients:
Chondroitin Sulfate, Boswellin, Yucca Powder, Manganese Ascorbate, Bromelain, Vitamin C, Omega 3 Fatty Acid, Omega 6 Fatty Acid, Vitamin A, Vitamin E
Price per day: $.91
Rating Rationale: A good amount of both forms of Glucosamine delivered by liquid, will ensure maximum absorption. The high quality Glucosamine, and 10 synergistic ingredients, have all been shown to aid in the fight against arthritis. The combination makes a very good product.

* Doctor and Veterinarian Recommended

Amount of Glucosamine per daily dose: 100 mg
Type of Glucosamine: Glucosamine Sulfate
Quality of Glucosamine: not known
Delivery System: Liquid
Synergistic Ingredients:
6 calories, 1.4 grams of Carbohydrate, 8 mg. of Vitamin C, 300 mg. of Mucopolysaccharides, 100 mg. of Glucosamine Potassium Sulfate, and 100 mg. of MSM (Methylsulfonylmethane). Other ingredients include Filtered Water, Fructose, Natural Flavors, Citric Acid, Red Cabbage Extract (for color), Sodium Benzoate (Preserves Freshness)
Price per day: $1.00
Rating rationale: A low amount of Glucosamine, unknown quality of ingredients, an alternate system of chondroitin delivery. The product has very little in it besides fruit flavoring. The thing this product has going for it is that it is in liquid form.

Glusoamine for arthritis pills
Amount of Glucosamine per daily dose: 2,100 mg
Type of Glucosamine: Glucosamine HCL
Quality of Glucosamine: pharmaceutical-grade
Delivery System: Liquid
Synergistic Ingredients:
600 mg of Chondroitin Sulfate, 600 mg of MSM, 1.9 mg of Manganese, 500mg of Vitamin C, 20 mg of Yucca, 15 mg of Boswellic Acid
Price per day: $1.06 - $2.12
Rating Rationale: A good mix of ingredients with a good supply of Glucosamine. The Glucosamine is Glucosamine HCL. It has MSM; there are very few studies of the effects of MSM on humans. Those who advocate using MSM to relieve arthritis pain say that you should take from 1,000 mg to 6,000 mg per day to realize its benefits. It also has a little Manganese, and 833% of the RDA of Vitamin C, which may cause a severely upset stomach for many. The very high price will rule it out for most budgets, but if you can afford it, it may give you some relief, seeing that it is in liquid form.

A note on MSM: There are very few studies of the effect of MSM on humans but some do show that MSM reduces inflammation and pain if taken in an adequate daily dosage. The human studies known to us are by Dr. Lawrence at UCLA, who gave the patients 2,250 mg per day (750 mg, 3 times per day) and by P.R. Usha who gave the patients 1,500 mg (500 mg, 3 times per day). If you are going to take MSM, it appears that large dosages may be necessary to experience any pain-reducing benefits it may have.

Juice glucosamine for arthritis
Joint Juice™

Joint Juice™
Amount of Glucosamine per daily dose: 1,500 mg
Type of Glucosamine: not stated
Quality of Glucosamine: not stated
Delivery System: Liquid
Synergistic Ingredients: 1,500 milligrams of Glucosamine and 60 milligrams of vitamin C, with real fruit juice.
Price per day: $1.00
Rating Rationale: A good supply of Glucosamine and vitamin C, however, besides those, there is very little in this product except fruit juice. It is an expensive novelty drink that provides an adequate supply of liquid Glucosamine but does not contain any additional anti-inflammatory or pain-relieving ingredients or ingredients having any synergistic beneficial effects.

The Capsule Products
Reminder: Liquid glucosamine absorbed more quickly, much more fully, and provides greater and longer lasting relief.

Due to this, we have given two ratings for the capsule products since we need to be comparing apples with apples. The overall rating is a rating that is compared to all products. The capsule rating is a rating as it stands among only products which provide glucosamine in pill form.

bad arthritis pain relief

*no picture provided

Cosamin DS™
Amount of Glucosamine per daily dose: 1,000 mg
Type of Glucosamine: Glucosamine HCL
Quality of Glucosamine: not stated
Delivery System: pill
Synergistic Ingredients: 800 mg Chondroitin Sulfate, 20mg Manganese, 132 mg Ascorbate
Price per daily dose: $.81 (varies slightly depending on retail outlet)
Rating Rationale: A good amount of Glucosamine. It is Glucosamine HCL. There is a good amount of Chondroitin, but 750% of the RDA of Manganese, which can be harmful and cause a high intensity of basal ganglia. In pill form, the Glucosamine HCL and chondroitin sulfate may not be absorbed very well and provide less than optimal pain relief.

The below capsule products are not recommended because they:

  • Failed independent testing
  • Contain a mixture of herbs not known to be safe
  • Put consumers at risk for lead/mercury contamination
  • Contain unproved substances

The below products are not highly recommended.

Capsule Products to Avoid:

  • Glucosamine Plus
  • Joint Care
  • Pain Free
  • Joint Fuel
  • Joint Rescue
  • Osteo-Joint
  • Can-Do

The Creams

There is growing evidence that glucosamine can actually be absorbed through the skin. For that reason, the makers of Synflex® also make available a topical analgesic which contains glucosamine.

Synflex® Power+Plus.

We recommend products that contain pharmaceutical level, high quality, liquid glucosamine sulfate or a mixture of both glucosamine sulfate and glucosamine HCL. The best products are also combined with ingredients that work synergistically with glucosamine to help rebuild cartilage, ease pain, reduce inflammation, and increase mobility. These include:

  • White Willow Bark
  • Chondroitin Sulfate
  • Boswellin
  • Yucca Powder
  • Manganese Ascorbate
  • Bromelain
  • Vitamin C
  • Omega 3 Fatty Acid
  • Omega 6 Fatty Acid
  • Vitamin A
  • Vitamin E

While the majority of research to date has been done on pill products, liquid products provide greater absorption and greater availability, meaning greater pain relief for osteoarthritis sufferers. Overall, there are a great many products that can assist, and it is wise to research and do your homework on what would be best for you.

As far as capsule products are concerned, we recommend Osteo-Bi-Flex and Cosamin DS, however, we recommend that first you try a liquid glucosamine product with the qualities described above for the reasons stated above.

As noted throughout this page, Synflex America, Inc. provides this information. Synflex America, Inc. believes that good quality liquid glucosamine products are more beneficial to osteoarthritis sufferers than are glucosamine pills, powders, capsules or tablets. Among the liquid glucosamine products, Synflex America believes that its product Synflex® is the best for the reasons stated above. You, of course, must exercise your own judgment about which product is the most beneficial at a reasonable cost.

You may also be interested in:

  • Glucosamine Blog

    Arthritis pain relief with Glucosamine Chondroitin. Syn-flex liquid Glucosamine Chondroitin for arthritis pain relief in people, pet arthritis in dogs and feline arthritis, and Synflex for athletes.

  • Dosage Info

    The daily dose of Synflex® for humans is 1/4 oz. We recommend doubling the dosage during the first ten days. For individuals weighing more than 220 pounds, you may wish to take a 1/2 oz. per day.

  • Liquid Glucosamine FAQ

    You have questions about liquid glucosamine and arthritis pain relief. We have answers.

  • Usage

    Learn how to measure Synflex's liquid glucosamine properly.

  • Ingredients

    Synflex has the ingredients we claim it has as shown by a random test of a number of Glucosamine products conducted by Consumer Labs several years ago.