Synflex 1500 Formula Case (12 Bottles) – Most popular!

Certified Ingredients Per 1/4 oz. of Synflex® 1500

  • 1500 mg Glucosamine HCL and Glucosamine Sulfate
  • 25 mg Chondroitin
  • 10 mg White Willow Bark
  • 8 mg Boswellin
  • 3 mg Yucca Powder
  • 5 mg Manganese (Ascorbate)
  • 1 mg Bromelain
  • 5 mg Vitamin C
  • 5 mg Omega 3 Fatty Acid
  • 1.67 mg Omega 6 Fatty Acid
  • 80 IU Vitamin A
  • 2 IU Vitamin E

*White willow bark is not aspirin. Nor, does it have the side effects which can be caused by aspirin.

$359.40 Per Case | Flavor: Orange | Size: 8 fl. oz.

SKU: 1002-1 Category:


Liquid Glucosamine Chondroitin Joint Health Supplement

Our popular liquid glucosamine chondroitin formula in its most powerful form.
The best supplement for athletes and anyone with joint problems.

No matter the reason for your joint pain and discomfort, it can become a burden and derail your confidence in doing what you love. We’ve created our Synflex 1500 formula to relieve the pain and improve your mobility. The formula contains 1,500 milligrams of glucosamine hydrochloride and glucosamine sulfate as well as 25 milligrams of chondroitin sulfate. We’ve included 10 additional ingredients to further support your joint health, making it a wonderful complement to your existing exercise routine and healthy diet.

Compared to the hundreds of glucosamine capsules, pills, and powders that are ineffective and not bioavailable, our strong liquid glucosamine chondroitin supplement has a high potency and bioavailability. With daily use, the benefits are long-lasting and likely to make a noticeable difference within just a couple of weeks. Synflex 1500 is the optimal solution for easing symptoms associated with damaged cartilage and inflamed joints. To maintain the effects and avoid running out of Synflex 1500, you can bulk order the supplement in a case of 12 bottles and receive a discount!

Supports Mobility and Joint Health

Glucosamine is crucial for building cartilage, and chondroitin is essential for improving the flow and absorption of cartilage nutrients. Synflex 1500 contains high amounts of both in order to have the maximum effect on your joint health and mobility. The addition of white willow bark assists with reducing levels of prostaglandins, which are compounds that can trigger inflammation, because it contains an ingredient called Salicin. With this combination, our liquid glucosamine chondroitin formula can combat sore and stiff joints so that you can get around better. It protects against harmful enzymes too, effectively reducing inflammation and pain.

Strong Pharmaceutical-Quality Liquid Glucosamine Supplement

For our Synflex 1500 liquid glucosamine formula, we’ve added several vitamins and minerals, including antioxidants and anti-inflammatory ingredients that provide a unique and beneficial synergistic blend. Some of these include fatty acids, yucca powder, and manganese. We only use ingredients of the highest quality. This variety gives your body the chemical compounds that it needs to repair cell damage, including cartilage reconstruction. The combination can even hinder premature aging.

High Bioavailability and Fast Absorption

One reason why powder and pill glucosamine chondroitin supplements are inferior to Synflex 1500 is that the body can’t absorb the key ingredients efficiently. It’s much easier for the body to absorb the liquid form of these nutrients. We’re proud to report that many individuals experience results in two weeks or less.

Delicious and Easy to Use

Glucosamine pills, tablets, and capsules can be hard to swallow and leave a bad taste in your mouth. Synflex 1500 has a great orange flavor, so it’s easy to take your daily dose. On top of that, you get the perfect dose every time by filling the innovative reservoir that’s built into our liquid glucosamine bottle.

All-Natural and Pure Ingredients

We produce Synflex 1500 in a GMP-certified facility in the United States. This means that our facility adheres to good manufacturing practices. You’ll only receive natural liquid glucosamine and chondroitin. Our formula never contains fillers or gluten and doesn’t cause adverse side effects. We also offer a 30-day, money-back guarantee on all bulk order cases of 12 Synflex 1500 bottles!

Ingredients Overview

  • 1500MG Glucosamine — Vital building blocks for cartilage.
  • 25 MG Chondroitin sulfate — Improves the flow and absorption of nutrients to boost cartilage resilience. May also block enzymes that damage cartilage.
  • 10MG Salicin (White Willow Bark) —Inhibits the production of inflammation-causing compounds.
  • Vitamins A, C, and E — Important antioxidants that defend against cell destruction.
  • Omega-3 and omega-6 — Fatty acids with anti-inflammatory properties that relieve joint discomfort.
  • Boswellic acid — Natural anti-inflammatory with anti-arthritic properties.
  • Bromelain — Restores fluid balance and reduces swelling in the joints.
  • Manganese — Contains ascorbate, which is essential for cartilage formation, joint lubrication, and bone growth.
  • Yucca powder — Has anti-inflammatory properties that ease arthritis pain.

Product Comparison

Synflex® Original vs. Synflex® 1500 Liquid Glucosamine Ingredients

Want to find out more about the difference between Synflex Original Formula and Synflex 1500 Formula?  Read our blog post.

* Synflex® 1500 is not recommended for pets.

FAQs About Synflex 1500

Questions and Answers about Glucosamine for Arthritis and Joints


We have taken the utmost care to provide both the highest-quality and most effective product on the market today. To do that, we only offer the finest quality and purest forms of ingredients. We use 98% pure liquid Glucosamine and a blend of other arthritis-fighting ingredients. As well, each batch of Synflex® undergoes a laboratory analysis to ensure ingredient quality and efficacy. Synflex® is manufactured in a GMP certified lab and each batch is issued a certificate of analysis.

Of interest, Synflex® was the first company to bring a pharmaceutical-quality liquid Glucosamine product to market on the internet. This, after two intensive years of work in the background development.

No. Synflex® is an all-natural product and there are no side effects.

Synflex® is an all-natural product and it should not interact with medications of any kind.

Synflex® is sold in a number of health food stores; chiropractic offices; veterinarian offices; health food stores; online retailers; and, the like. However, Synflex® is not available in any large retail stores at this time. We prefer to deal directly with our customers and as the exclusive dealer, we are able to offer the best prices.

You can order online via our secure server or, you can call us at 1-800-796-0142. If you are outside of the United States, you can call 1-941-778-2155 or place your order online.

When your cartilage is damaged, either by primary osteoarthritis or secondary osteoarthritis (after an injury) you are going to pay a price. Cartilage protects the bones from coming into contact with one another and if they do, it is extremely painful.

Whether as a result of aging; overuse; genetics; or, injury, some 40 million Americans suffer from Osteoarthritis. An estimated 10 million remain undiagnosed. Worldwide, the number is about 350 million who have OA.

Glucosamine is a charged sugar molecule that is a key component of the extracellular matrix of cartilage (grout between the cartilage cells). It absorbs and releases water with every step you take and when it does, it acts as a ‘shock absorber’ for your joints.

Glucosamine is a natural sugar produced by your body. It is the essential and principal ingredient that determines the quantity of proteoglycans (water-holding) molecules that also form in your body. The greater the amount of glucosamine in your body, the greater the number of proteoglycans. Proteoglycans are large, water-binding molecules made up of both proteins and sugars. It is important to understand that they are the major building block of vital and healthy cartilage.

Glucosamine products are nutritional supplements and are not regulated by the Food and Drug Administration (FDA). However, Synflex® is manufactured in the United States with (USA) pharmaceutical-quality ingredients, in an NSF cGMP certified facility. This means that our lab is in full compliance with the requirements of Good Manufacturing Practices. This system ensures that the procedures and documentation of the product represents quality. A Certificate of Analysis accompanies each batch which ensures that each ingredient represented is in compliance with stated measurements and specifications.

It is advisable to maintain a daily dose of ¼ oz. (1.5 teaspoons) per day. Those who are over 220 pounds may wish to maintain a higher dose than that. (1/2 oz. per day) If you believe that your arthritis does not warrant a full daily dose or, if you are taking Synflex® as some way to help keep your cartilage healthy you may want to drop your dose by half of what you had been taking.

If you want faster results, we recommend doubling your daily dose (one in the morning and one in the evening) for the first 7-10 days. Then, dropping back to a single dose a day.

You can take Synflex® as long as glucosamine has not been a problem in the past. The antigen in shellfish that causes the allergic reaction to shellfish has been removed from Synflex®. Nonetheless, we recommend you consult with your physician before using Synflex®.

  • In fact, new research indicates that glucosamine is unlikely to cause an allergic reaction in someone who has an allergy. In most cases, allergies are caused by proteins in shellfish and not chitin, a carbohydrate from which glucosamine is extracted. Furthermore, there is no crossover between the acid derived chitin from shells and the antigens that cause shellfish allergies. The reason? The acid process required to leach the chitin from the shell strips away the carbohydrate side chains that would be antigenic.

Synflex® 1500 has an all-natural citrus orange flavor.

Synflex 1500® is not recommended for pets due to the extra anti-inflammatory ingredient added to Synflex 1500 known as white willow bark.  Instead, for pets there are two formulas to choose from. The Original formula has a tart, berry flavor. We also have a beef flavor available for pets.

  • The Synflex® 1500 formula (the page you are viewing right now) is recommended for humans and athletes only. It contains contains 1,500 mg. of glucosamine in a ¼ oz. serving along with the added boost of white willow bark — a natural anti-inflammatory ingredient that has been used in pain remedies since 1823. Synflex 1500 is orange flavored, and our only formula to include white willow bark.
  • The Synflex® Original formula can be used by both humans and for family pets. It contains 1,250 mg. of glucosamine in a ¼ oz. serving and has a berry flavor and is an excellent first introduction to liquid glucosamine if you haven’t used a glucosamine supplement before.
  • The Synflex® Beef formula contains 1,500 mg. of glucosamine in a ¼ oz. serving. So, if your pet is clearly demonstrating soreness or is lame, you might opt for the beef formula just to gain the extra amount of glucosamine.
  • We have had great success with pets, including those with hip dysplasia.

    • A cautionary note: Do not use Synflex® 1500 for your pets.

    Yes, Synflex Original and especially Synflex 1500 can benefit athletes greatly. Tennis, running, golf, and contact sports make your joints take a lot of abuse.

  • The repetitive motions and increased stress that you put on your joints wear down the cartilage, which is the spongy substance that cushions the ends of your bones so that they don’t grind together. Cartilage can wear out faster because of an active lifestyle.
  • Synflex contains the ingredients glucosamine and chondroitin, which work collectively to help combat the wear and tear in your joints.
  • Best of all our liquid pharmaceutical-quality formula offers high bioavailability so that your body absorbs 80% to 85% of the ingredients. Glucosamine chondroitin pills and powders only offer 15% to 20% absorption.
  • You can see what athletes have to say about Synflex® here.

    Synflex America, Inc. was founded in 1999 by J. R. Rogers. In 1993, he fell off a two-story building. After surgery, he had spinal stenosis and secondary arthritis in his neck. He tried every product he could find but nothing helped.

    A friend of his was using a prototype liquid glucosamine formula for thoroughbred horses. And, he gave some to J. R. to see what results he would get. It was an incredible moment. J. R. began passing out samples to his friends and they are astounded by the results they were getting. The constant positive feedback convinced him that this product had to be in the hands of every person who suffered for arthritis (OA).

    • He began the process of modifying the product for human use and soon, Synflex America became the vehicle to bring it to market. In July of 2001, Synflex® was introduced to the general public worldwide. It has been an incredible success story with a rapidly growing audience of direct purchasers and wholesale buyers. In fact, Synflex America, Inc. is the largest direct-to-consumer retailer of liquid glucosamine in the world.

    Actually, many doctors have begun recommending glucosamine for their OA patients and some indeed, are naming Synflex® as the product to try. In these cases, it is likely that their patients have reported their success using it. You can read a number of their testimonials in our success stories.

  • The recommended daily dosage for humans is 1/4 of an ounce per day of liquid glucosamine formula Synflex®. You may wish to double the dose during the first 10 days to a 1/2 oz. for maximum effectiveness and arthritis relief.
  • If you are over 230 pounds, you may find that staying with a 1/2 oz. daily dosage works more effectively.
  • For further information, we have set up a page that lays out dosing of Synflex®. You can view that page right here. View the dosage information page.
  • Certainly, the ingredients themselves play a major role here. Synflex® uses pharmaceutical-quality ingredients. As well, the liquid formula allows the body to absorb the product much faster.

    Yes, it does. In fact, clinical testing has indicated that the power of glucosamine is more effective when used with chondroitin.

    You do not have to refrigerate Synflex®. You can store it at room temperature unlike some products on the market. The darkening in color is nothing more than light striking the Synflex® bottle which in turn, darkens the liquid. (Oxidation)

    When this happens, the formula appears darker but it tastes the same and is still effective until the expiration date on the bottle.

    Additional information

    Weight 160 oz
    Dimensions 12 × 8 × 7 in
    Bottle Size

    8 fl. oz.