Glucosamine Differences: Synflex, Instaflex, Beneflex

Which is a better arthritis

Synflex made a promise to the public (more importantly, our customers) at the beginning of the year and again at the beginning of May in honor of Arthritis Awareness Month, to provide quality service and to always be honest. That is what we are doing today.

Let’s talk about Instaflex and Beneflex. These are two supplements claiming to help alleviate arthritis pain. We looked at their ingredients, and they do contain known substances that promote joint health.  Let’s go into a bit more detail.


Instaflex is a joint supplement primarily sold at GNC. A bottle of Instaflex contains 30 pills. You are advised to take 3 pills a day. A bottle costs $69.99. So you get a 10 day supply for $69.99.  Instaflex comes with a free trial. After your trail, you automatically get charged $69.99 and get automatic shipments of Instaflex. You have to call to cancel after your trail; otherwise your credit card gets charged.


Glucosamine Sulfate

1,500 mg

Methylsulfonlylmethane (MSM)

500 mg

White Willow Bark Extract

250 mg

  (Standardized to 15% salicin)
Ginger Root Concentrate 4:1

250 mg

Boswellia Serrata Extract

125 mg

  (Standardized to 65% boswellic acid)
Turmeric Root Extract

50 mg

  (Standardized to 95% curcumin)
Cayenne 40m H.U.

50 mg

Hyaluronic Acid

4 mg


Beneflex is also a joint supplement. Direct Digital, the company who owns Instaflex, recently launched Beneflex. You get 30 pills for $59.99. Serving is one pill per day. It’s slightly cheaper than Instaflex. The difference is that Beneflex does not contain glucosamine.


Hyaluronic Acid 90%

5 mg

UC-II® (providing 10mg undenatured type II collagen)

40 mg

AprèsFlex® – Boswellia Serrata Extract

100 mg

Turmeric Extract 25:1 (standardized to 95% curcuminoids)

200 mg


Direct Digital, makers of both Instaflex and Beneflex proudly boasts this on

“Beneflex’s entire formula fills in just a single capsule. With no Glucosamine or other fillers.”

They are making several claims here.

  1. Glucosamine is a filler
  2. Glucosamine doesn’t work

Now scroll back up to Instaflex. What do you see listed first as an ingredient?

That’s right. Glucosamine Sulfate.

So what Direct Digital is really inferring is that their own product doesn’t work, which is true. Reviews (not the ones they select for their website) show that Instaflex doesn’t really work. Instaflex reviews on Amazon are mediocre at best. So you can see why Direct Digital came up with a new formula and new product since their original is a bust.

Glucosamine Sulfate Works

Now, doctors and nutritionists agree that glucosamine sulfate works. After all, glucosamine is a natural substance found in our body. The Instaflex formula may not be quite right, but glucosamine sulfate works.

Synflex uses glucosamine sulfate. Our reviews on Amazon are really good.

Pill vs Liquid and Value

Several things make Synflex different from Instaflex and Beneflex.

  1. Synflex uses pharmaceutical quality glucosamine. That’s why Synflex works. Our glucosamine is good quality.
  2. Synflex is a liquid. Absorption rate for liquid supplements are 80%. Your body gets to use the nutrients faster.
  3. Synflex is a better value. An 8 oz bottle of Synflex costs $28.85 with free shipping in the US. A bottle of Instaflex that only lasts 10 days costs $69.99; 30-day supply of Beneflex is $59.99. It’s obvious isn’t it?

So you decide. Do you go for gimmicks? Or do you want something that actually works?